Journal: Heliyon

Article Title: The value of contrast-enhanced magnetic resonance imaging for diagnosis of extrahepatic cholangiocarcinoma

doi: 10.1016/j.heliyon.2023.e23448

Figure Lengend Snippet: Images in a 48-year-old man with pathologically-proven extrahepatic cholangiocarcinoma (white arrows). (A) Pre-enhanced T1 weighted imaging shows a mild-hyperintensity lesion. The lesion presents mild hyperenhancement in the (B) arterial phase and it gradually peaks in the (C) portal venous phase and (D) transitional phase. (E) Axial T2 weighted imaging demonstrates an isointense tumor. Signal intensity of the lesion on (F) diffusion weighted imaging is unequivocally higher than the uninvolved bile duct wall, and that on (G) apparent diffusion coefficient map is unequivocally lower than the uninvolved bile duct wall. (F) Magnetic resonance cholangiopancreatography depicts filling defects with severely dilated bile ducts.

Article Snippet: The baseline contrast-enhanced MRI examination include (a) T2-weighted imaging (T2WI); (b) magnetic resonance cholangiopancreatography; (c) diffusion-weighted imaging (DWI) (b values: 0, 50, 500, 800, 1000, and 1200 s/mm2 [Siemens MAGNETOM Skyra]; 0, 50, 1000 s/mm2 [uMR588]; 0, 50, 800, 1000 s/mm2 [Siemens Avanto]; 0, 50, 600 s/mm2 [Siemens TrioTim]) with apparent diffusion coefficient (ADC) maps reconstructed by monoexponential model. (d) T1-weighted in-phase and opposed-phase imaging; (e) dynamic T1-weighted imaging (T1WI) before and after injection of contrast agent in the arterial phase (AP), portal venous phase (PVP), transitional phase (TP) (for hepatobiliary contrast agent) or the delayed phase (DP) (for extracellular contrast agent).

Techniques: Imaging, Diffusion-based Assay

Journal: Frontiers in Oncology

Article Title: Paclitaxel Chemotherapy Elicits Widespread Brain Anisotropy Changes in a Comprehensive Mouse Model of Breast Cancer Survivorship: Evidence From In Vivo Diffusion Weighted Imaging

doi: 10.3389/fonc.2022.798704

Figure Lengend Snippet: Paclitaxel chemotherapy consistently increased fractional anisotropy following the final dose in survivor mice. Axial, sagittal, and coronal views of fractional anisotropy probability maps calculated from diffusion weighted imaging are shown. Paclitaxel n=8, vehicle n=8. Unpaired parametric two-tailed t tests were used for statistical analyses. Nonparametric Mann-Whitney U tests were used when the assumptions of normality and equal variances were not met.

Article Snippet: Diffusion weighted imaging (DWI) was conducted at The Ohio State University small animal imaging core (Columbus, OH, USA) using a 9.7 T BioSpec 94/30 horizontal bore magnet (Bruker, Billerica, MA, USA) with a mouse brain phased array coil and ParaVisionTM 5.1 software.

Techniques: Diffusion-based Assay, Imaging, Two Tailed Test, MANN-WHITNEY

Journal: SAGE Open Medicine

Article Title: Stroke-related restless leg syndrome in hemorrhagic and ischemic stroke patients

doi: 10.1177/20503121251336900

Figure Lengend Snippet: Stroke lesions in the brain area on MRI. (a) Lesion in thalamus showed on MRI–DWI. (b) Lesion in thalamus showed on MRI–ADC image. (c) Lesion on putamen showed on MRI–DWI. (d) Lesion on thalamus indicated on MRI–ADC image. ADC: apparent diffusion coefficient; DWI: diffusion-weighted imaging; MRI: magnetic resonance imaging.

Article Snippet: All patients were evaluated by brain magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI) at 1.5 T (Siemens, Erlangen, Germany) within 7 days after the onset of symptoms to confirm acute ischemic or hemorrhagic stroke.

Techniques: Diffusion-based Assay, Imaging, Magnetic Resonance Imaging